
NIH scientists identify new brain mechanism involved in impulsive cocaine-seeking in rats
Muscarinic acetylcholine M2 receptors regulate lateral habenula neuron activity and control cocaine seeking behavior

Muscarinic acetylcholine M2 receptors regulate lateral habenula neuron activity and control cocaine seeking behavior
What’s New at NIDA NIDA Diversity Scholars Travel Award Program In person conferences have started back up! The National Institute on Drug Abuse (NIDA…
Primary prevention, including screening and intervention, is relatively inexpensive
Despite decline, smoking cessation efforts still critical for people with substance use or other psychiatric disorders
What’s New at NIDA NIDA Inviting Input on Racial Equity Initiative Action Plan The National Institute on Drug Abuse (NIDA) invites your feedback on…
Screening for substance use disorder in teens may predict adult prescription drug use and misuse and prevent overdose
This graph highlights growing, dangerous trend, particularly for people new to drug use
NIH-supported research highlights growing, dangerous trend, particularly for people new to drug use
Racism is rampant in the US with effects that are pervasive and wide-ranging, including in the areas of science and health. In 2020, in response to…
Better characterizing clinical features of self-injury is critical to provide support and effective treatments
Often fatal, endocarditis remains a dangerous but largely unknown health threat for people who inject drugs
Often fatal, endocarditis remains a dangerous but largely unknown health threat for people who inject drugs
Highlights basic information about infective endocarditis alongside an anatomical image of a human heart
What’s New at NIDA NDSN Reunion Event On January 26, the NIDA Office of Diversity and Health Disparities (ODHD) hosted the first ever virtual NIDA…
Study emphasizes the importance of screening for suicidality and providing treatment to people with mental illnesses and substance use disorders
NIH-supported study also found girls were at higher risk for stress, anxiety, and depression than boys
Data from the Justice Community Opioid Innovation Network (JCOIN) support providing this treatment in justice settings
Fentanyl is a synthetic opioid that is approximately 50 times more potent than morphine
This month saw drug overdose deaths in the U.S. surpass an unthinkable milestone: 100,000 deaths in a year
NIDA Director Dr. Nora Volkow offers a year-end message of hope during the holiday season
This study reported that hallucination-like perceptions in mice were associated with elevated dopamine levels in the striatum. Blocking dopamine with…
What’s New at NIDA Notice of High-Priority Training Areas NIDA recently published a Notice describing High-Priority Research Areas for T32 Training…
Results from the 2021 Monitoring the Future Survey report substance use behaviors and related attitudes among adolescents in the U.S.
A recent NIDA-funded study provides a potential explanation for the increased vulnerability to smoking-related health effects among Black people.
NIDA presents a new web video series on research, compassion, and HIV services for people who use drugs
This study found that in New York State, people living with HIV were more likely to be diagnosed with, hospitalized for, and die in hospital from…
Paul was a coach, advocate, and one of the leading voices for the HEALing Communities Study
This study found that collaborations between physicians with buprenorphine waivers and community pharmacists in the treatment of patients with opioid…
Dr. Nora Volkow writes about her personal experience with stigma and the need for a large-scale social intervention to change public attitudes toward…
A NIDA-funded study found that people with some types of substance dependence exhibited less rightward asymmetry of the nucleus accumbens than did…
Leaders from across the NIH will brief reporters about on research efforts related to COVID-19 and SARS-CoV-2
This study found that people with hepatitis C virus (HCV) who inject drugs, offering buprenorphine treatment for opioid use disorder at the same…
Opioid drugs affect not only the brain and, consequently, behavior, but also numerous other body systems whose cells carry opioid receptors, including…
By changing the activity of this circuit, researchers restored levels of motivation in a pre-clinical model of pain tested in rodents
What’s New at NIDA Congratulations 2021 NIDA Diversity Scholars Network (NDSN) Program Scholars! The NDSN program is a competitive, rigorous, and…
NIH study highlights the need to expand buprenorphine-based treatment while monitoring and reducing misuse
The HEALthy Brain and Child Development study will answer longstanding early development questions
Co-occurring health disorders appear to contribute to increased risk, NIH study suggests
To help combat the stigma that still attaches to HIV, we have decided to rename the AIDS Research Program to the HIV Research Program.
Epigenetic changes that can persist for generations after nicotine exposure may predispose children and grandchildren of people who smoke to develop…
Patterns of methamphetamine use have become riskier, diversified across U.S. population
CDC Alert on the Increased availability of cannabis products containing delta-8 tetrahydrocannabinol (THC) and the potential for adverse events
Children with greater access to resources, better social support, and better perinatal health had larger brain surface areas and higher cognitive…
NIH-supported study underscores the need for racially inclusive approach to address the opioid crisis in hard-hit areas
Annual NIH-supported study reports changing substance use trends among college students and college-aged adults
More people died of overdoses in the U.S. in 2020 than in any other one-year period. These data are shouting for change.
Directors highlight research results from NIH-funded science and community partnerships
Specific cocaine-induced decreases in gray matter density were associated with reduced performance on tests of memory and cognition.
Adolescents experiencing stress, mental health issues, and hardship most likely to use substances
People who experienced more childhood adversity had higher rates of substance use in late adolescence.
Las normas de nuestra sociedad que rodean el consumo de drogas y la drogadicción continúan alimentándose de conceptos erróneos y mitos infundados
This year the NIDA Summer Research Internship Program received over 500 applications! A record high of 83 students were accepted into the program, the…
Addressing the impact of caregiver deaths critical for pediatric mental health, authors note
Children of invervention recipients showed improved developmental functioning before age 5, as well as fewer problem behaviors; better academic…
Appropriate terminology can improve how people with these conditions are treated in health care settings and society
Study finds treatment is safe and well tolerated in people with opioid use disorder experiencing withdrawal symptoms
Marijuana use and drinking did not significantly change during the COVID-19 pandemic, despite record decreases in the substances’ perceived…
Simultaneous alcohol and marijuana use is associated with both increased alcohol consumption and greater negative consequences.
NIH study suggests a link between cannabis use and higher levels of suicidal ideation, plan, and attempt
Substance use disorders (SUDs) increase a person’s risk for becoming severely ill from COVID-19, making vaccinations vital.
Researchers identified optimal intervention combinations for six cities (one-quarter of all people with HIV in the U.S.).
Trial underway to determine whether mobile clinics can help improve health outcomes for people with opioid use disorder
What’s New at NIDA Bringing Data Science to Addiction Research Did you know NIDA hosted a 4-part Data Science Careers Seminar Series in the Spring of…
Fewer overdose deaths occurred among adults treated with opioid agonist medications than among those not treated with medication.
New guidance for researchers establishes a standard THC unit of 5 milligrams.
NIH leaders emphasize the importance of patient voices in addiction medication development
A public health approach to drug addiction is critical for population well-being and health equity
Study adds to a growing body of evidence that prenatal exposure to cannabis may be associated with poor birth outcomes
For most assessed cognitive functions, the negative correlation remained after controlling for age, gender, socioeconomic status, and sleep.
What’s New at NIDA Ending Structural Racism: The NIH UNITE Initiative The UNITE initiative was established to identify and address structural racism…
Explore the different types of medications prescribed for opioid overdose, withdrawal, and addiction
Remembering Dr. Mary Jeanne Kreek, a great addiction pioneer and longtime NIDA grantee.
Inhibition of KORs using a short-acting selective antagonist significantly prevented escalation of cocaine intake in rats during chronic exposure and…
NIH analysis measures the prevalence of nine substance use disorders after first substance use or misuse in young people
Use of pre-exposure prophylaxis to prevent contracting HIV increased among men who have sex with men from 2013 to 2017.
Including previously reported cases, there are now at least 19 U.S. deaths associated with poppy seeds in the literature.
Analysis of illegal drug confiscations in five key U.S. regions suggests new drug supply patterns since COVID-19
NIH Director Francis Collins announces UNITE, an NIH-wide initiative to end structural racism in biomedical science
Finding better ways to reach people at higher risk of HIV for testing and engagement with HIV prevention and treatment services is a critical…
Preventing cocaine memories from re-strengthening in an unstable period following retrieval attenuates cocaine seeking.
Expert report cites unequal progress in Southern U.S. and among marginalized groups
Inherent in the mission of NIH is that biomedical research and its application can and should benefit all people
The ORTDD Team wishes our research training community a Happy New Year! What’s New at NIDA The NIDA Data Science Notice of Special Interest has hit…
Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes
Daily, PrEP (pre-exposure prophylaxis medication), is proven to prevent HIV transmission from injection drug use or sex.
Only 1 percent of the providers who prescribe opioids account for almost half of all opioid doses prescribed and one-quarter of opioid prescriptions…
NIH-supported study finds biggest increase among American Indians and Alaska Natives
People with a substance use disorder (SUD) at any time in their lives are 1.5 times more likely to contract COVID-19 than those without an SUD, and…
A combination of bupropion and naltrexone successfully reduced methamphetamine use
Combination medication may be effective in treating adults with methamphetamine use disorder
NIH-supported pilot study found team-based approach may improve buprenorphine care
Animal studies suggest that subjects with HIV who suffer from opioid use disorders may have higher viral reservoirs in the central nervous system than…
Los pacientes en tratamiento para el trastorno por consumo de opioides que se sentían más cómodos tomando decisiones cuando no conocían la…
These reviews address how each of these addictive substances and HIV individually or collectively affect the immune system and subsequent clinical and…
Los hallazgos indican que los niveles de vapeo de nicotina y marihuana no aumentaron desde 2019 hasta principios de 2020, aunque siguen siendo altos.
On December 15, the National Institute on Drug Abuse announced new data from the annual Monitoring the Future study conducted by researchers at the…
NIDA-funded research aims to help understand teen drug use and its effects
What’s New at NIDA NIDA Career Workshop Recap NIDA hosted a virtual Career Workshop on November 9th, 2020 for Graduate Students, Postdocs, and Early…
Un conjunto específico de neuronas en la amígdala basolateral se activaba cuando los ratones experimentaban dolor.